Beebs says:
Ghost, what did you mean by the polio vaccine being political, etc.? I seem to recall that there may be some possibilities where it's reemerged lately or something. But, are you saying it was totally unnecessary? I'm just confused.
I said the
Sabin vaccine was political. The
Salk vaccine was developed 1st. It works the "usual" way vaccines do; you get injected subcutaneously with an attenuated (not able to make you sick) polio virus, which sparks your body's immune system to make antibodies to the polio virus. Then, when it meets the real-thing polio virus, it starts manufacturing antibodies & clobbers it & you don't get polio.
I don't know about the Salk vaccine itself in this next regard, but these days most virus vaccines don't even use the whole virus, even a completely non-viable whole virus; they use parts of the virus's outer coat, which generally are the things that provoke the immune response. The part of the virus you want to
avoid transmitting, if you can, is the DNA (or RNA, if its an RNA-based virus). That's the part that lets the virus take over your cells' machinery to reproduce itself. They didn't know all this back in the 50s.
The Sabin vaccine by contrast is a viable mutant form of the polio virus which supposedly isn't able to give you polio. You eat it. On little sugar cubes, in my case. The mutant form of polio hangs out in your stomach, occupying sites that real polio would like to occupy, but can't because this mutant harmless form is lurking there.
There are a lot of problems with viable virus, even supposedly harmless forms of viable virus. There are recorded examples of this stuff back-mutating & giving people real polio. There are recorded examples of this stuff back-mutating & giving real polio to kids' parents, who had no defense against it because they hadn't been given either form of vaccine.
Sabin had a lot of friends in high places who basically rail-roaded use of his vaccine through. I can see arguments for using one vaccine
instead of the other; I can see no reason why people like myself, who had
already been given the Salk vaccine, & could probably have demonstrated our immunity to polio at the time (of course, to do it in a test tube would require today's medical tests, which of course they didn't have in '58 or whatever) to have to be given the Sabin vaccine.
That's what I mean by "political".
And, of course, look at what started this discussion; that a supposedly harmless (except for the people for whom its deadly, of course) childhood disease like chicken pox turns out to live on in your body & in later years give you very dangerous shingles. I dunno what that supposedly harmless Sabin-vaccine polio virus living in my stomach could do.